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CA Cancer J Clin 2002; 52:23
doi: 10.3322/canjclin.52.1.23
© 2002 American Cancer Society
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 Cancer Statistics, 2002
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Cancer Statistics, 2002

Ahmedin Jemal, DVM, PhD, Andrea Thomas, MPH, Taylor Murray and Michael Thun, MD, MS

Dr. Jemal is Program Director for Cancer Occurrence, Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA.
Ms. Thomas is Manager, Surveillance Information Services, Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA.
Mr. Murray is Manager, Surveillance Data Systems, Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA.
Dr. Thun is Vice President for Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA.

Every year the American Cancer Society estimates the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data on cancer incidence, mortality, and survival, using National Cancer Institute (NCI) incidence and National Center for Health Statistics (NCHS) mortality data. Incidence and death rates are age adjusted to the 1970 US standard population. It is estimated that 1,284,900 new cases of cancer will be diagnosed and 555,500 people will die from cancer in the United States in the year 2002. From 1992 to 1998, cancer death rates declined in males and females, while cancer incidence rates decreased among males and increased slightly among females. Most notably, African-American men showed the largest decline for both incidence and mortality. Nevertheless, African Americans still carry the highest burden of cancer with later-stage cancer diagnosis and poorer survival compared with whites. Despite the continued decline in cancer death rates, the total number of recorded cancer deaths in the United States continues to increase slightly due to the aging and expanding population.




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G. Brandacher, A. Perathoner, R. Ladurner, S. Schneeberger, P. Obrist, C. Winkler, E. R. Werner, G. Werner-Felmayer, H. G. Weiss, G. Gobel, et al.
Prognostic Value of Indoleamine 2,3-Dioxygenase Expression in Colorectal Cancer: Effect on Tumor-Infiltrating T Cells
Clin. Cancer Res., February 15, 2006; 12(4): 1144 - 1151.
[Abstract] [Full Text] [PDF]

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 Clin. Cancer Res.Home page
J. S. Schleypen, N. Baur, R. Kammerer, P. J. Nelson, K. Rohrmann, E. F. Grone, M. Hohenfellner, A. Haferkamp, H. Pohla, D. J. Schendel, et al.
Cytotoxic Markers and Frequency Predict Functional Capacity of Natural Killer Cells Infiltrating Renal Cell Carcinoma
Clin. Cancer Res., February 1, 2006; 12(3): 718 - 725.
[Abstract] [Full Text] [PDF]

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 Proc. Natl. Acad. Sci. USAHome page
J. R. McWhirter, A. Kretz-Rommel, A. Saven, T. Maruyama, K. N. Potter, C. I. Mockridge, E. P. Ravey, F. Qin, and K. S. Bowdish
Antibodies selected from combinatorial libraries block a tumor antigen that plays a key role in immunomodulation
PNAS, January 24, 2006; 103(4): 1041 - 1046.
[Abstract] [Full Text] [PDF]

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 JCOHome page
C. Tournigand, A. Cervantes, A. Figer, G. Lledo, M. Flesch, M. Buyse, L. Mineur, E. Carola, P.-L. Etienne, F. Rivera, et al.
OPTIMOX1: A Randomized Study of FOLFOX4 or FOLFOX7 With Oxaliplatin in a Stop-and-Go Fashion in Advanced Colorectal Cancer--A GERCOR Study
J. Clin. Oncol., January 20, 2006; 24(3): 394 - 400.
[Abstract] [Full Text] [PDF]

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 GutHome page
P Veit, C Kuhle, T Beyer, H Kuehl, C U Herborn, G Borsch, H Stergar, J Barkhausen, A Bockisch, and G Antoch
Whole body positron emission tomography/computed tomography (PET/CT) tumour staging with integrated PET/CT colonography: technical feasibility and first experiences in patients with colorectal cancer
Gut, January 1, 2006; 55(1): 68 - 73.
[Abstract] [Full Text] [PDF]

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 EndocrinologyHome page
J. A. Magee, L.-w. Chang, G. D. Stormo, and J. Milbrandt
Direct, Androgen Receptor-Mediated Regulation of the FKBP5 Gene via a Distal Enhancer Element
Endocrinology, January 1, 2006; 147(1): 590 - 598.
[Abstract] [Full Text] [PDF]

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 CarcinogenesisHome page
D. Wei, M. Kanai, S. Huang, and K. Xie
Emerging role of KLF4 in human gastrointestinal cancer
Carcinogenesis, January 1, 2006; 27(1): 23 - 31.
[Abstract] [Full Text] [PDF]

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 JCOHome page
S. Tauro, C. Craddock, K. Peggs, G. Begum, P. Mahendra, G. Cook, J. Marsh, D. Milligan, A. Goldstone, A. Hunter, et al.
Allogeneic Stem-Cell Transplantation Using a Reduced-Intensity Conditioning Regimen Has the Capacity to Produce Durable Remissions and Long-Term Disease-Free Survival in Patients With High-Risk Acute Myeloid Leukemia and Myelodysplasia
J. Clin. Oncol., December 20, 2005; 23(36): 9387 - 9393.
[Abstract] [Full Text] [PDF]

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 Clin. Cancer Res.Home page
T. Zhang, H.-C. Sun, Y. Xu, K.-Z. Zhang, L. Wang, L.-X. Qin, W.-Z. Wu, Y.-K. Liu, S.-L. Ye, and Z.-Y. Tang
Overexpression of Platelet-Derived Growth Factor Receptor {alpha} in Endothelial Cells of Hepatocellular Carcinoma Associated with High Metastatic Potential
Clin. Cancer Res., December 15, 2005; 11(24): 8557 - 8563.
[Abstract] [Full Text] [PDF]

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 Ann. Surg. Oncol.Home page
M. Reinblatt, R. H. Pin, W. J. Bowers, H. J. Federoff, and Y. Fong
Herpes Simplex Virus Amplicon Delivery of a Hypoxia-Inducible Soluble Vascular Endothelial Growth Factor Receptor (sFlk-1) Inhibits Angiogenesis and Tumor Growth in Pancreatic Adenocarcinoma
Ann. Surg. Oncol., December 1, 2005; 12(12): 1025 - 1036.
[Abstract] [Full Text] [PDF]

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 ChestHome page
C. L. Nguyen, W. J. Scott, N. A. Young, T. Rader, L. R. Giles, and M. Goldberg
Radiofrequency Ablation of Primary Lung Cancer: Results From an Ablate and Resect Pilot Study
Chest, November 1, 2005; 128(5): 3507 - 3511.
[Abstract] [Full Text] [PDF]

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 Clin. Cancer Res.Home page
H. Takeuchi, J. Kim, A. Fujimoto, N. Umetani, T. Mori, A. Bilchik, R. Turner, A. Tran, C. Kuo, and D. S.B. Hoon
X-Linked Inhibitor of Apoptosis Protein Expression Level in Colorectal Cancer Is Regulated by Hepatocyte Growth Factor/C-Met Pathway via Akt Signaling
Clin. Cancer Res., November 1, 2005; 11(21): 7621 - 7628.
[Abstract] [Full Text] [PDF]

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 Clin. Cancer Res.Home page
M. T. Hueman, Z. A. Dehqanzada, T. E. Novak, J. M. Gurney, M. M. Woll, G. B. Ryan, C. E. Storrer, C. Fisher, D. G. McLeod, C. G. Ioannides, et al.
Phase I Clinical Trial of a HER-2/neu Peptide (E75) Vaccine for the Prevention of Prostate-Specific Antigen Recurrence in High-Risk Prostate Cancer Patients
Clin. Cancer Res., October 15, 2005; 11(20): 7470 - 7479.
[Abstract] [Full Text] [PDF]

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 Cancer Res.Home page
S. Banerjee, Y. Zhang, S. Ali, M. Bhuiyan, Z. Wang, P. J. Chiao, P. A. Philip, J. Abbruzzese, and F. H. Sarkar
Molecular Evidence for Increased Antitumor Activity of Gemcitabine by Genistein In vitro and In vivo Using an Orthotopic Model of Pancreatic Cancer
Cancer Res., October 1, 2005; 65(19): 9064 - 9072.
[Abstract] [Full Text] [PDF]

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 Clin. Cancer Res.Home page
S. A. Belinsky, D. M. Klinge, J. D. Dekker, M. W. Smith, T. J. Bocklage, F. D. Gilliland, R. E. Crowell, D. D. Karp, C. A. Stidley, and M. A. Picchi
Gene Promoter Methylation in Plasma and Sputum Increases with Lung Cancer Risk
Clin. Cancer Res., September 15, 2005; 11(18): 6505 - 6511.
[Abstract] [Full Text] [PDF]

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 JCOHome page
H. Choy, A. Nabid, B. Stea, C. Scott, W. Roa, L. Kleinberg, J. Ayoub, C. Smith, L. Souhami, S. Hamburg, et al.
Phase II Multicenter Study of Induction Chemotherapy Followed by Concurrent Efaproxiral (RSR13) and Thoracic Radiotherapy for Patients With Locally Advanced Non-Small-Cell Lung Cancer
J. Clin. Oncol., September 1, 2005; 23(25): 5918 - 5928.
[Abstract] [Full Text] [PDF]

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 RadiologyHome page
F. Wu, Z.-B. Wang, H. Zhu, W.-Z. Chen, J.-Z. Zou, J. Bai, K.-Q. Li, C.-B. Jin, F.-L. Xie, and H.-B. Su
Feasibility of US-guided High-Intensity Focused Ultrasound Treatment in Patients with Advanced Pancreatic Cancer: Initial Experience
Radiology, September 1, 2005; 236(3): 1034 - 1040.
[Abstract] [Full Text] [PDF]

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 J. Biol. Chem.Home page
A. Herman-Antosiewicz and S. V. Singh
Checkpoint Kinase 1 Regulates Diallyl Trisulfide-induced Mitotic Arrest in Human Prostate Cancer Cells
J. Biol. Chem., August 5, 2005; 280(31): 28519 - 28528.
[Abstract] [Full Text] [PDF]

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 Clin. Cancer Res.Home page
T. Arumugam, D. M. Simeone, K. Van Golen, and C. D. Logsdon
S100P Promotes Pancreatic Cancer Growth, Survival, and Invasion
Clin. Cancer Res., August 1, 2005; 11(15): 5356 - 5364.
[Abstract] [Full Text] [PDF]

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 J. Biol. Chem.Home page
U. K. Misra, R. Deedwania, and S. V. Pizzo
Binding of Activated {alpha}2-Macroglobulin to Its Cell Surface Receptor GRP78 in 1-LN Prostate Cancer Cells Regulates PAK-2-dependent Activation of LIMK
J. Biol. Chem., July 15, 2005; 280(28): 26278 - 26286.
[Abstract] [Full Text] [PDF]

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 Clin. Cancer Res.Home page
T. Friess, W. Scheuer, and M. Hasmann
Combination Treatment with Erlotinib and Pertuzumab against Human Tumor Xenografts Is Superior to Monotherapy
Clin. Cancer Res., July 15, 2005; 11(14): 5300 - 5309.
[Abstract] [Full Text] [PDF]

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 Proc. Natl. Acad. Sci. USAHome page
J. E. Ippolito, J. Xu, S. Jain, K. Moulder, S. Mennerick, J. R. Crowley, R. R. Townsend, and J. I. Gordon
An integrated functional genomics and metabolomics approach for defining poor prognosis in human neuroendocrine cancers
PNAS, July 12, 2005; 102(28): 9901 - 9906.
[Abstract] [Full Text] [PDF]

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 ChestHome page
C. M. Mery, A. N. Pappas, R. Bueno, Y. L. Colson, P. Linden, D. J. Sugarbaker, and M. T. Jaklitsch
Similar Long-term Survival of Elderly Patients With Non-small Cell Lung Cancer Treated With Lobectomy or Wedge Resection Within the Surveillance, Epidemiology, and End Results Database
Chest, July 1, 2005; 128(1): 237 - 245.
[Abstract] [Full Text] [PDF]

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 CarcinogenesisHome page
D. J. Waters, S. Shen, L. T. Glickman, D. M. Cooley, D. G. Bostwick, J. Qian, G. F. Combs Jr, and J. S. Morris
Prostate cancer risk and DNA damage: translational significance of selenium supplementation in a canine model
Carcinogenesis, July 1, 2005; 26(7): 1256 - 1262.
[Abstract] [Full Text] [PDF]

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 Clin. Cancer Res.Home page
H. Kohno, R. Suzuki, S. Sugie, H. Tsuda, and T. Tanaka
Dietary Supplementation with Silymarin Inhibits 3,2'-Dimethyl-4-Aminobiphenyl-Induced Prostate Carcinogenesis in Male F344 Rats
Clin. Cancer Res., July 1, 2005; 11(13): 4962 - 4967.
[Abstract] [Full Text] [PDF]

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 JCOHome page
A. Raval, D. M. Lucas, J. J. Matkovic, K. L. Bennett, S. Liyanarachchi, D. C. Young, L. Rassenti, T. J. Kipps, M. R. Grever, J. C. Byrd, et al.
TWIST2 Demonstrates Differential Methylation in Immunoglobulin Variable Heavy Chain Mutated and Unmutated Chronic Lymphocytic Leukemia
J. Clin. Oncol., June 10, 2005; 23(17): 3877 - 3885.
[Abstract] [Full Text] [PDF]

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 GutHome page
T R Levin, F A Farraye, R E Schoen, G Hoff, W Atkin, J H Bond, S Winawer, R W Burt, D A Johnson, L M Kirk, et al.
Quality in the technical performance of screening flexible sigmoidoscopy: recommendations of an international multi-society task group
Gut, June 1, 2005; 54(6): 807 - 813.
[Abstract] [Full Text] [PDF]

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 ChestHome page
R. Barrera, W. Shi, D. Amar, H. T. Thaler, N. Gabovich, M. S. Bains, and D. A. White
Smoking and Timing of Cessation: Impact on Pulmonary Complications After Thoracotomy
Chest, June 1, 2005; 127(6): 1977 - 1983.
[Abstract] [Full Text] [PDF]

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 Clin. Cancer Res.Home page
M. Bonham, J. Posakony, I. Coleman, B. Montgomery, J. Simon, and P. S. Nelson
Characterization of Chemical Constituents in Scutellaria baicalensis with Antiandrogenic and Growth-Inhibitory Activities toward Prostate Carcinoma
Clin. Cancer Res., May 15, 2005; 11(10): 3905 - 3914.
[Abstract] [Full Text] [PDF]

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 Cancer Epidemiol. Biomarkers Prev.Home page
A. Stone, L. D. Ratnasinghe, G. L. Emerson, R. Modali, T. Lehman, G. Runnells, A. Carroll, W. Carter, S. Barnhart, A. A. Rasheed, et al.
CYP3A43 Pro340Ala Polymorphism and Prostate Cancer Risk in African Americans and Caucasians
Cancer Epidemiol. Biomarkers Prev., May 1, 2005; 14(5): 1257 - 1261.
[Abstract] [Full Text] [PDF]

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 Journal of the American Dental AssociationHome page
G. D. CRUZ, J. S. OSTROFF, J. V. KUMAR, and S. GAJENDRA
Preventing and detecting oral cancer: Oral health care providers' readiness to provide health behavior counseling and oral cancer examinations
J Am Dent Assoc, May 1, 2005; 136(5): 594 - 601.
[Abstract] [Full Text] [PDF]

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 Cancer Res.Home page
Y. Zhang, S. Banerjee, Z.-w. Wang, D. J. Marciniak, A. P.N. Majumdar, and F. H. Sarkar
Epidermal Growth Factor Receptor-Related Protein Inhibits Cell Growth and Induces Apoptosis of BxPC3 Pancreatic Cancer Cells
Cancer Res., May 1, 2005; 65(9): 3877 - 3882.
[Abstract] [Full Text] [PDF]

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 Am. J. Public HealthHome page
S. N. Zenk, A. J. Schulz, B. A. Israel, S. A. James, S. Bao, and M. L. Wilson
Neighborhood Racial Composition, Neighborhood Poverty, and the Spatial Accessibility of Supermarkets in Metropolitan Detroit
Am J Public Health, April 1, 2005; 95(4): 660 - 667.
[Abstract] [Full Text] [PDF]

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 Toxicol PatholHome page
A. W. Suttie, G. E. Dinse, A. Nyska, G. J. Moser, T. L. Goldsworthy, and R. R. Maronpot
An Investigation of the Effects of Late-Onset Dietary Restriction on Prostate Cancer Development in the TRAMP Mouse
Toxicol Pathol, April 1, 2005; 33(3): 386 - 397.
[Abstract] [Full Text] [PDF]

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 Mol. Cell. ProteomicsHome page
R. Chen, S. Pan, T. A. Brentnall, and R. Aebersold
Proteomic Profiling of Pancreatic Cancer for Biomarker Discovery
Mol. Cell. Proteomics, April 1, 2005; 4(4): 523 - 533.
[Abstract] [Full Text] [PDF]

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 BloodHome page
A. J. Johnson, L. L. Smith, J. Zhu, N. A. Heerema, S. Jefferson, A. Mone, M. Grever, C.-S. Chen, and J. C. Byrd
A novel celecoxib derivative, OSU03012, induces cytotoxicity in primary CLL cells and transformed B-cell lymphoma cell line via a caspase- and Bcl-2-independent mechanism
Blood, March 15, 2005; 105(6): 2504 - 2509.
[Abstract] [Full Text] [PDF]


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